NFL odds, lines, picks, spreads, best bets, predictions, office pool, optimal survivor picks for Week 17, 2022

The NFL playoff picture will start taking shape following multiple elimination games during the Week 17 NFL schedule. One of those games features Tampa Bay vs. Carolina in an NFC South showdown on Sunday. The Panthers are 6-9 this season, but they could jump into first place in the division with a win over the 7-8 Buccaneers. Tampa Bay is a four-point home favorite in the latest Week 17 NFL odds at Caesars Sportsbook. New Orleans will try to keep its slim divisional hopes alive as well when it travels to Philadelphia as a 5.5-point underdog in the NFL spreads. Which NFL bets, NFL office pool picks, and NFL survivor picks should you make? All of the Week 17 NFL lines are listed below, and SportsLine’s advanced computer model has all the NFL betting advice and predictions you need to make the best Week 17 NFL picks now.

The model, which simulates every NFL game 10,000 times, is up well over $7,000 for $100 players on top-rated NFL picks since its inception. The model enters Week 17 of the 2022 NFL season on an incredible 158-113 run on top-rated NFL picks that dates back to the 2017 season.

The model also ranked in the top 10 on NFLPickWatch four of the past six years on straight-up NFL picks and beat more than 94% of CBS Sports Football Pick’em players four times during that span. Anyone who has followed it is way up.

Now, it has turned its attention to the latest Week 17 NFL odds and locked in NFL picks for every NFL matchup. Head here to see every pick.

Top Week 17 NFL predictions

One of the model’s strongest Week 17 NFL picks is that the Patriots (-2.5) cover the spread at home against the Dolphins. Miami’s strong season has come to a crashing halt, as the Dolphins wrapped up a winless December with a 26-20 loss to Green Bay on Christmas Day. They also suffered losses to the 49ers, Chargers and Bills earlier in the month, putting their NFL playoff bracket hopes in limbo. New England has a chance to jump back into the AFC playoff picture on Sunday, as the Patriots are currently the first team outside the projected postseason bracket in the AFC.

Miami head coach Mike McDaniel confirmed Wednesday that starting quarterback Tua Tagovailoa sustained a concussion in the loss to the Packers, so he will be sidelined this week. New England’s defense has not allowed more than 30 points in four straight games, holding Cincinnati’s offense to 22 points last week. SportsLine’s model projects Miami to score just 17 points in this matchup, as the Patriots are covering the spread in well over 60% of simulations. See which other teams to pick here.

Top Week 17 NFL survivor picks

The model’s Week 17 NFL knockout pool picks say to avoid the Buccaneers, even though they are favorites versus the Panthers. Tampa Bay needed a late rally to escape with a win at Arizona in overtime last week despite entering the game as a 7.5-point favorite. The Buccaneers have been struggling to take care of business throughout the season, covering the spread just one time in their last nine home games.

They only need to win outright for survivor pool purposes, but the model is not high on Tampa Bay’s trustworthiness right now. Quarterback Tom Brady has thrown six interceptions in his last three games, creating a recipe for an underdog to pull off an upset. Carolina has been trending in the right direction, winning three of its last four games. The Panthers are coming off an upset win against Detroit last week and the model believes they have a chance to spring another upset on Sunday. See which team you should pick here.

Top Week 17 NFL office pool picks

One of the strongest Week 17 NFL football pool picks from the model is that the Lions beat the Bears. Chicago’s eight-game losing streak is tied for the longest in franchise history and it has allowed at least 25 points in each game during the streak. Meanwhile, Detroit already boasts a top-five offense in terms of points and yards, so this matchup will be one team’s strength against another’s weakness.

Jared Goff is on the best stretch of his career, as he has 12 touchdowns versus zero picks over his last seven games. Now, he faces a Bears defense that has allowed its last two opposing quarterbacks to account for three touchdowns apiece. Detroit must win to keep its playoff hopes alive, so it has an incentive that Chicago doesn’t. The model projects the Lions to win in 70% of simulations. See which other teams to pick here.

How to make Week 17 NFL picks

The model has made the call on who wins and covers in every other game on the Week 17 NFL schedule, and it’s calling for a shocking loss by a division leader. It’s also backing a surprising team that’s turned the corner in its NFL survivor picks. You can only get every pick for every game at SportsLine.

So what NFL predictions, NFL pool picks, and NFL survivor picks can you make with confidence? And which division leader goes down hard? Check out the latest NFL odds below, then visit SportsLine to see which teams win and cover the spread, all from a proven computer model that has returned well over $7,000 since its inception, and find out.

Week 17 NFL odds, lines, spreads

Get full NFL picks at SportsLine

Sunday, Jan. 1

Cardinals at Falcons (-5.5, 41.5)

Featured Game | Atlanta Falcons vs. Arizona Cardinals

Bears at Lions (-6, 52.5)

Featured Game | Detroit Lions vs. Chicago Bears

Jaguars at Texans (+3, 43)

Featured Game | Houston Texans vs. Jacksonville Jaguars

Broncos at Chiefs (-12.5, 45)

Featured Game | Kansas City Chiefs vs. Denver Broncos

Dolphins at Patriots (-2.5, 41)

Featured Game | New England Patriots vs. Miami Dolphins

Colts at Giants (-5.5, 39)

Featured Game | New York Giants vs. Indianapolis Colts

Saints at Eagles (-5.5, 41.5)

Featured Game | Philadelphia Eagles vs. New Orleans Saints

Panthers at Buccaneers (-4, 40.5)

Featured Game | Tampa Bay Buccaneers vs. Carolina Panthers

Browns at Commanders (-2, 41)

Featured Game | Washington Commanders vs. Cleveland Browns

49ers at Raiders (+9.5, 42.5)

Featured Game | Las Vegas Raiders vs. San Francisco 49ers

Jets at Seahawks (+1.5, 42.5)

Featured Game | Seattle Seahawks vs. New York Jets

Vikings at Packers (-3.5, 47.5)

Featured Game | Green Bay Packers vs. Minnesota Vikings

Rams at Chargers (-6.5, 42)

Featured Game | Los Angeles Chargers vs. Los Angeles Rams

Steelers at Ravens (-2, 35.5)

Featured Game | Baltimore Ravens vs. Pittsburgh Steelers

Monday, Jan. 2

Bills at Bengals (+1.5, 50)

Featured Game | Cincinnati Bengals vs. Buffalo Bills

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